Memantine is a prescription medicine that works as an NMDA‑type glutamate receptor antagonist. In simple terms, it protects brain cells from excess glutamate, which can damage neurons over time. Doctors mainly prescribe it for moderate to severe Alzheimer’s disease, but it’s also used for other types of dementia and sometimes for off‑label conditions like Parkinson’s‑related cognitive decline.
The usual starting dose is 5 mg once a day, taken with or without food. After a week, the dose typically goes up by 5 mg each day until you reach the target dose of 20 mg twice daily (40 mg total). Some people stay on a lower dose if they feel side effects, and your doctor will adjust it based on how you respond.
Swallow the tablets whole – don’t crush or chew them – because breaking the tablet can change how the drug is released and may increase side effects. If you miss a dose, take it as soon as you remember, but if it’s almost time for the next dose, just skip the missed one and continue with your regular schedule.
Most people tolerate memantine well, but you might notice dizziness, headaches, constipation, or a mild feeling of confusion, especially when you first start. These usually settle down after a few days. If you experience severe nausea, vomiting, hallucinations, or an unusual increase in anxiety, call your doctor right away – these could signal a reaction that needs medical attention.
Because memantine works on the brain’s chemistry, it can interact with other medicines that affect the central nervous system, such as certain antidepressants, antipsychotics, or strong painkillers. Always give your pharmacist a full list of what you’re taking, including over‑the‑counter supplements.
If you need to order memantine online, stick to pharmacies that require a valid prescription and have a physical address, clear contact info, and a licensed pharmacist on staff. Look for reviews that mention real‑world experiences, and avoid sites that promise “no prescription needed” – that’s a red flag for counterfeit pills.
Check the price against local pharmacy rates; huge discounts can mean low‑quality or expired medication. Also, verify that the pharmacy follows secure payment methods and offers a clear return or refund policy if something goes wrong.
When the package arrives, inspect the labeling and packaging for any signs of tampering. The tablets should match the description you ordered (strength, shape, and imprint). If anything looks off, contact the pharmacy immediately and consider reporting the issue to your national drug safety agency.
Memantine can be a helpful part of a dementia treatment plan, but it works best when you follow dosing guidelines, watch for side effects, and get it from a trusted source. Talk with your doctor about any questions you have, and never share your medication with others.
Clear 2025 guide to memantine: what it does, who benefits, dosing, side effects, and when to stop. Evidence-backed, practical tips for patients and caregivers.
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